Genes May Help Explain Why People Respond Differently to GLP-1 Drugs​Genes May Help Explain Why People Respond Differently to GLP-1 Drugs 

This Medical News article discusses findings that genetic variants may affect patients’ responses to glucagon-like peptide-1 receptor agonists such as semaglutide and tirzepatide. ​This Medical News article discusses findings that genetic variants may affect patients’ responses to glucagon-like peptide-1 receptor agonists such as semaglutide and tirzepatide. 

Tirzepatide improves blood sugar control in metformin-refractory type 2 diabetes​Tirzepatide improves blood sugar control in metformin-refractory type 2 diabetes 

1. In this randomized controlled trial, tirzepatide produced substantially greater reductions in HbA1c, body weight, waist circumference, and BMI than intensified conventional care (ICC) in adults with early type 2 diabetes inadequately controlled on metformin. 2. A significantly higher proportion of participants treated with tirzepatide, compared with ICC, achieved normoglycemia (HbA1c <5.7%). Evidence Rating Level: Read More

Scientists discover why Ozempic and Wegovy weight loss eventually plateaus​Scientists discover why Ozempic and Wegovy weight loss eventually plateaus 

New NIH research reveals that semaglutide sparks different responses inside appetite-controlling brain cells, offering fresh insight into why GLP-1 weight-loss drugs don’t work the same for everyone. Scientists also found a possible way to extend the drugs’ effects, potentially helping patients push past weight-loss plateaus. ​New NIH research reveals that semaglutide sparks different responses inside Read More

AI scans 400,000 Reddit posts and finds hidden Ozempic side effects​AI scans 400,000 Reddit posts and finds hidden Ozempic side effects 

By analyzing over 400,000 Reddit posts, researchers discovered that users of popular GLP-1 weight-loss drugs frequently discussed unexpected symptoms like menstrual irregularities, chills, and hot flashes. The findings suggest AI could turn social media into a powerful early-warning system for spotting side effects that clinical trials may miss. ​By analyzing over 400,000 Reddit posts, researchers Read More

From high BMI to the ‘GLP-1 look’: how weight-loss jabs are changing the face of beauty​From high BMI to the ‘GLP-1 look’: how weight-loss jabs are changing the face of beauty 

Experts say exponential growth in the use of drugs such as Wegovy is shifting our perception of what is attractive Mona Lisa is the most famous portrait ever painted and millions of people flock to the Louvre to admire her enigmatic smile every year. As well as being beautiful, Mona Lisa was, according to some Read More