Oral GLP-1s without fasting or reduced efficacy: Delivery approach protects peptide-based drugs from stomach acid​Oral GLP-1s without fasting or reduced efficacy: Delivery approach protects peptide-based drugs from stomach acid 

Biomedical engineers at Duke University have developed a new approach to delivering GLP-1 medications orally that does not require fasting and maintains their efficacy. The technique could also be useful for any pharmaceutical based on peptides such as insulin or treatments for irritable bowel syndrome, HIV and osteoporosis. ​Biomedical engineers at Duke University have developed Read More

Sentinel lymph node biopsy may reduce the need for axillary dissection in cN1 breast cancer​Sentinel lymph node biopsy may reduce the need for axillary dissection in cN1 breast cancer 

1. Upfront sentinel lymph node biopsy permitted the avoidance of axillary lymph node dissection in most patients with cN1 HR+/HER2- breast cancer and limited ultrasound findings. 2. Sentinel lymph node biopsy was feasible in this population, with no short-term instances of isolated axillary or locoregional recurrence. Evidence Rating Level: 2 (Good) Study Rundown: Axillary lymph
The post Sentinel lymph node biopsy may reduce the need for axillary dissection in cN1 breast cancer first appeared on 2 Minute Medicine. Source: 2 Minute Medicine

GLP-1s vs Bariatric Surgery; Obesity Trends Reversing; Creatine for Menopause?​GLP-1s vs Bariatric Surgery; Obesity Trends Reversing; Creatine for Menopause? 

(MedPage Today) — GLP-1 medication use increased by 140.4% from 2022 to 2024 while metabolic bariatric surgery utilization declined by 34.1%, national insurance data indicated. (JAMA Surgery) Generic forms of semaglutide (Ozempic, Wegovy) aren… ​ (MedPage Today) — GLP-1 medication use increased by 140.4% from 2022 to 2024 while metabolic bariatric surgery utilization declined by Read More