FDA approves Enhertu as neoadjuvant, adjuvant treatment for breast cancerFDA approves Enhertu as neoadjuvant, adjuvant treatment for breast cancer

The U.S. Food and Drug Administration has approved AstraZeneca’s Enhertu (fam-trastuzumab deruxtecan-nxki) for both the neoadjuvant and adjuvant treatment of patients with human epidermal growth factor receptor 2 (HER2)-positive early breast cancer.
Once-Weekly Semaglutide in Adults With Daily Cigarette UseOnce-Weekly Semaglutide in Adults With Daily Cigarette Use
This randomized clinical trial evaluates the effects of semaglutide vs placebo on cigarette smoking, craving, and weight outcomes in people who smoke. This randomized clinical trial evaluates the effects of semaglutide vs placebo on cigarette smoking, craving, and weight outcomes in people who smoke.
Genes May Help Explain Why People Respond Differently to GLP-1 DrugsGenes May Help Explain Why People Respond Differently to GLP-1 Drugs
This Medical News article discusses findings that genetic variants may affect patients’ responses to glucagon-like peptide-1 receptor agonists such as semaglutide and tirzepatide. This Medical News article discusses findings that genetic variants may affect patients’ responses to glucagon-like peptide-1 receptor agonists such as semaglutide and tirzepatide.
Tirzepatide improves blood sugar control in metformin-refractory type 2 diabetesTirzepatide improves blood sugar control in metformin-refractory type 2 diabetes

1. In this randomized controlled trial, tirzepatide produced substantially greater reductions in HbA1c, body weight, waist circumference, and BMI than intensified conventional care (ICC) in adults with early type 2 diabetes inadequately controlled on metformin. 2. A significantly higher proportion of participants treated with tirzepatide, compared with ICC, achieved normoglycemia (HbA1c <5.7%). Evidence Rating Level: Read More
When bariatric surgery may lower cancer risk: Insulin, sex and genes offer new cluesWhen bariatric surgery may lower cancer risk: Insulin, sex and genes offer new clues

Substantial and sustained weight loss has been linked to a reduced risk of cancer and cancer-related death, mainly in women. Two new studies now provide clues to why the risk is reduced—and suggest that gender, metabolism and genetics may play a crucial role.
Scientists discover why Ozempic and Wegovy weight loss eventually plateausScientists discover why Ozempic and Wegovy weight loss eventually plateaus

New NIH research reveals that semaglutide sparks different responses inside appetite-controlling brain cells, offering fresh insight into why GLP-1 weight-loss drugs don’t work the same for everyone. Scientists also found a possible way to extend the drugs’ effects, potentially helping patients push past weight-loss plateaus. New NIH research reveals that semaglutide sparks different responses inside Read More
AI scans 400,000 Reddit posts and finds hidden Ozempic side effectsAI scans 400,000 Reddit posts and finds hidden Ozempic side effects

By analyzing over 400,000 Reddit posts, researchers discovered that users of popular GLP-1 weight-loss drugs frequently discussed unexpected symptoms like menstrual irregularities, chills, and hot flashes. The findings suggest AI could turn social media into a powerful early-warning system for spotting side effects that clinical trials may miss. By analyzing over 400,000 Reddit posts, researchers Read More
Doctors Reveal The Most Common Side Effects Of GLP-1s — And How To Manage ThemDoctors Reveal The Most Common Side Effects Of GLP-1s — And How To Manage Them

Ozempic, Wegovy and other GLP-1 medications are popular but can cause unwanted health concerns. Ozempic, Wegovy and other GLP-1 medications are popular but can cause unwanted health concerns.
Vanessa Trump calls Tiger Woods her ‘strength’ amid breast cancer diagnosis in touching social media postVanessa Trump calls Tiger Woods her ‘strength’ amid breast cancer diagnosis in touching social media post

Vanessa Trump posts emotional tribute to boyfriend Tiger Woods and her family, calling them her strength amid her breast cancer diagnosis and treatment.
People On GLP-1s Are Sharing The 1 Unexpected Obsession They Didn’t ExpectPeople On GLP-1s Are Sharing The 1 Unexpected Obsession They Didn’t Expect

“I thought about it for days.” View Entire Post › “I thought about it for days.” View Entire Post ›