Technology receives FDA approval for breast cancer treatmentTechnology receives FDA approval for breast cancer treatment

More than a decade ago, Yale chemist Craig Crews founded a biotechnology company in New Haven based on his pioneering research into PROTACs (or PROteolysis TArgeting Chimera), a technology that treats certain types of cancer and other diseases by degrading the proteins that cause them.
Teens With T1D, Obesity Reaped Benefits of GLP-1s, Case Studies SuggestTeens With T1D, Obesity Reaped Benefits of GLP-1s, Case Studies Suggest

(MedPage Today) — Two insulin-dependent adolescents with type 1 diabetes and obesity had metabolic improvements after starting a low-dose GLP-1 agent, a case series showed. One year after adding injectable semaglutide (Ozempic, Wegovy) to lifestyle… (MedPage Today) — Two insulin-dependent adolescents with type 1 diabetes and obesity had metabolic improvements after starting a low-dose Read More
Gut microbiota play a role in metabolic health after bariatric surgery, finds studyGut microbiota play a role in metabolic health after bariatric surgery, finds study

Changes in gut microbiota after bariatric surgery are strongly linked to altered metabolic health and sustained improvement in type 2 diabetes, according to a study led by researchers at the University of Gothenburg.
Scientists discover why Ozempic works better for some peopleScientists discover why Ozempic works better for some people

Some people taking Ozempic-like diabetes drugs may be getting dramatically better results for a surprising reason: why they overeat in the first place. A year-long study in Japan found that people who tend to eat because tempting food looks or smells irresistible were much more likely to lose weight and improve blood sugar levels on Read More
Common inflammatory genes link pancreatic cancer with obesity and diabetesCommon inflammatory genes link pancreatic cancer with obesity and diabetes

New research shows that the same genes are active in pancreatic cancer, obesity and diabetes, helping to explain why people with metabolic disease often face poorer cancer outcomes and pointing to future ways to predict recurrence and develop more targeted treatments.
Stopping GLP-1 drugs can quickly erase cardiovascular benefitsStopping GLP-1 drugs can quickly erase cardiovascular benefits

Following a rapid increase in popularity of GLP-1 drugs for diabetes and weight loss, such as semaglutide and tirzepatide, approximately one in eight U.S. adults now take these medications, which also provide cardiovascular benefits. However, when patients stop taking these drugs, they not only regain weight, but, according to a new study, they also incur Read More
New study identifies how obesity-related liver cancer becomes more aggressive and resistant to treatmentNew study identifies how obesity-related liver cancer becomes more aggressive and resistant to treatment

A research team affiliated with UNIST has made a significant discovery explaining why liver cancers associated with obesity and metabolic disorders tend to be more aggressive and less responsive to conventional treatments. The study reveals that a specific signaling pathway involving endotrophin—a protein secreted during liver fibrosis—and the receptor protein CD44 promotes tumor malignancy and drug resistance.
GLP-1 drugs and pregnancy: Who may face higher preterm birth riskGLP-1 drugs and pregnancy: Who may face higher preterm birth risk

Weight loss drugs have been linked to an increased risk of premature births among women who took them inadvertently just before or during early pregnancy to treat pre-existing diabetes. However, a large study of over 750,000 pregnancies found that there was no link to preterm births or other obstetric complications if the medication was being Read More
Discussing Recurrence Risk and Survivorship in Breast CancerDiscussing Recurrence Risk and Survivorship in Breast Cancer

(MedPage Today) — In “Beyond Diagnosis: Breast Cancer,” Cleveland Clinic oncologist Tiffany Onger, MD, and host John Mangels continue their conversations on communicating effectively and empathetically with patients across the breast cancer care…
WH Chief of Staff Susie Wiles Diagnosed With Breast CancerWH Chief of Staff Susie Wiles Diagnosed With Breast Cancer

White House chief of staff Susie Wiles announced on Monday that she has been diagnosed with breast cancer in the past week. She said she will continue to remain at the White House during her unspecified treatment. NBC’s Kelly O’Donnell reports for TODAY.