Semaglutide may improve motivation with major depressive disorderSemaglutide may improve motivation with major depressive disorder

Treatment with semaglutide significantly improves measures of motivation in patients with major depressive disorder (MDD), according to a study published April 29 in JAMA Psychiatry. Treatment with semaglutide significantly improves measures of motivation in patients with major depressive disorder (MDD), according to a study published April 29 in JAMA Psychiatry.
GLP-1 Drug Linked to Cases of Rare Vision-Altering ConditionGLP-1 Drug Linked to Cases of Rare Vision-Altering Condition

(MedPage Today) — Two patients taking the GLP-1 receptor agonist dulaglutide (Trulicity) developed choroidal lymphoid hyperplasia (CLH), a rare, benign condition of the uveal tract, that resolved after the patients stopped the drug. In both cases… (MedPage Today) — Two patients taking the GLP-1 receptor agonist dulaglutide (Trulicity) developed choroidal lymphoid hyperplasia (CLH), a Read More
Breast cancer cells with doubled genomes may dodge immunotherapy by turning off key immune signalsBreast cancer cells with doubled genomes may dodge immunotherapy by turning off key immune signals

An epigenetic mechanism by which tumors manage to hide from the body’s immune defenses has just been described by an international scientific team led by the University of Liège and the Dana-Farber Cancer Institute. These findings open up avenues for new therapeutic strategies combining epigenetics and immunotherapy. The paper is published in the journal Cancer Cell.
Cheaper generic Ozempic is coming soon — but not for AmericansCheaper generic Ozempic is coming soon — but not for Americans

India got it earlier this year, and Canada approved it last month. But when is the United States going to get a generic version of Ozempic? India got it earlier this year, and Canada approved it last month. But when is the United States going to get a generic version of Ozempic?
Continuing tirzepatide at full dose helps preserve weight loss over 112 weeksContinuing tirzepatide at full dose helps preserve weight loss over 112 weeks

New research presented at the European Congress on Obesity (ECO 2026) in Istanbul, Turkey (12–15 May) and published in The Lancet shows that people who have lost weight using the maximum tolerated dose (MTD) of tirzepatide are seven times more likely to maintain that weight loss by continuing on MTD than those who stop treatment, Read More
A 13-gene panel may help predict response to chemotherapy in triple-negative breast cancerA 13-gene panel may help predict response to chemotherapy in triple-negative breast cancer

Researchers at The University of Texas MD Anderson Cancer Center have characterized cancer cell-specific features in the tumor microenvironment (TME) of early-stage triple-negative breast cancer (TNBC) tissues, identifying specific macrophage subtypes associated with chemotherapy response.
How do weight-loss drugs like Mounjaro and Wegovy work?How do weight-loss drugs like Mounjaro and Wegovy work?

Wegovy and Mounjaro are available to certain patients on the NHS, and can also be bought privately. Wegovy and Mounjaro are available to certain patients on the NHS, and can also be bought privately.
Study on GLP-1s and Breast Cancer ‘Too Good to Be True’?Study on GLP-1s and Breast Cancer ‘Too Good to Be True’?

(MedPage Today) — Use of GLP-1 receptor agonists in breast cancer patients was linked to lower mortality and recurrence risk in a retrospective study, but experts are questioning the quality of the underlying data. At 10 years, the risk of all… (MedPage Today) — Use of GLP-1 receptor agonists in breast cancer patients was Read More
Metastatic Breast Cancers on the Rise, U.S. Study ShowsMetastatic Breast Cancers on the Rise, U.S. Study Shows

(MedPage Today) — Despite improvements in survival, the incidence of stage IV breast cancer increased significantly from 2010 through 2021, according to a U.S. population-based cohort study.
The age-adjusted incidence rate of de novo stage IV…
FTC Blocked From Endocrine Society Probe; FDA-Tzield Drama; GLP-1 Gene Therapy?FTC Blocked From Endocrine Society Probe; FDA-Tzield Drama; GLP-1 Gene Therapy?

(MedPage Today) — A federal judge blocked the Federal Trade Commission (FTC) from investigating the Endocrine Society and World Professional Association for Transgender Health, which support gender-affirming care in minors. (Reuters via… (MedPage Today) — A federal judge blocked the Federal Trade Commission (FTC) from investigating the Endocrine Society and World Professional Association for Read More