New blood-based biomarkers could help predict bariatric surgery outcomes in teensNew blood-based biomarkers could help predict bariatric surgery outcomes in teens
A USC-led team has developed an innovative way to predict blood pressure outcomes after bariatric surgery that outperforms the current standard practice. In 108 adolescents who underwent bariatric surgery, the researchers used blood tests taken before the procedure to predict which patients would have improved blood pressure five years later. The study is one of the first to use cutting-edge “omics” techniques, which analyze the body’s small molecules and proteins, to predict long-term health outcomes.
Trastuzumab Deruxtecan Scores Two Wins in HER2-Positive Early Breast CancerTrastuzumab Deruxtecan Scores Two Wins in HER2-Positive Early Breast Cancer
(MedPage Today) — BERLIN — The antibody-drug conjugate (ADC) trastuzumab deruxtecan (T-DXd, Enhertu) delivered impressive results in different HER2-positive early-stage breast cancer settings in back-to-back randomized clinical trials.
In…
STAT+: At ESMO, AstraZeneca, Gilead square off in triple-negative breast cancerSTAT+: At ESMO, AstraZeneca, Gilead square off in triple-negative breast cancer
AstraZeneca and Gilead both reported successful trials in a hard-to-treat form of breast cancer, sparking a debate about which drug may be better.
How cutting lipids could starve breast cancerHow cutting lipids could starve breast cancer
Researchers found that triple-negative breast cancer cells are “addicted” to lipids, a feature tied to obesity. By studying mice, they discovered that high lipid levels alone accelerate tumor growth. Lowering these fats slowed cancer progression, suggesting that lipid-lowering treatments could help. The findings also caution against high-fat diets such as keto for patients with obesity.
First Survival Win for CDK4/6 Inhibitors in High-Risk Early-Breast CancerFirst Survival Win for CDK4/6 Inhibitors in High-Risk Early-Breast Cancer
(MedPage Today) — BERLIN — For the first time in a phase III trial, adjuvant treatment with a CDK4/6 inhibitor significantly improved overall survival (OS) in high-risk early breast cancer, data reported here showed.
Patients who received…
STAT+: Enhertu pushes into early breast cancer, as antibody-drug conjugates move up the lineSTAT+: Enhertu pushes into early breast cancer, as antibody-drug conjugates move up the line
Enhertu can help patients with breast cancer when given earlier in the disease, according to data presented at the ESMO Conference 2025.
Surgery beats Ozempic for long-term health, Cleveland Clinic findsSurgery beats Ozempic for long-term health, Cleveland Clinic finds
Weight-loss surgery dramatically outperformed GLP-1 medications in improving longevity and reducing heart, kidney, and eye complications for people with obesity and diabetes. Over 10 years, patients lost far more weight and required fewer medications. Experts say surgery continues to offer survival advantages even in the age of potent obesity drugs. Weight-loss surgery dramatically outperformed GLP-1 Read More
Woman diagnosed with breast cancer at 27 after almost ignoring symptomWoman diagnosed with breast cancer at 27 after almost ignoring symptom
Marissa Coreno didn’t think anything about the lump under her armpit at first, until an ultrasound showed something worrying.
Woman diagnosed with breast cancer at 27 after almost ignoring warning signWoman diagnosed with breast cancer at 27 after almost ignoring warning sign
Marissa Coreno thought the bump in her armpit was nothing, but colleagues encouraged her to check it out. Tests found Stage II breast cancer. Coreno underwent aggressive treatment — and found love along the way.
STAT+: Roche, Celcuity detail successful advanced breast cancer studiesSTAT+: Roche, Celcuity detail successful advanced breast cancer studies
Roche and Celcuity each detailed positive advanced breast cancer trials at ESMO, studies that could lead to new approvals.