Dual GIP/GLP-1 Drug Linked to Fewer Deaths in Real-World Liver Disease Study​Dual GIP/GLP-1 Drug Linked to Fewer Deaths in Real-World Liver Disease Study 

(MedPage Today) — PHOENIX — Use of tirzepatide (Mounjaro, Zepbound) was associated with significantly lower risks of death, hospitalization, and major cardiovascular events compared with semaglutide (Ozempic, Wegovy) in high-risk patients with… ​ (MedPage Today) — PHOENIX — Use of tirzepatide (Mounjaro, Zepbound) was associated with significantly lower risks of death, hospitalization, and major cardiovascular Read More

Discovery of breast cancer treatment resistance mechanism could lead to new hope for some​Discovery of breast cancer treatment resistance mechanism could lead to new hope for some 

Mayo Clinic researchers have discovered a key reason why certain breast cancers might not respond to an important new class of therapeutics called antibody drug conjugates (ADCs). These treatments pair an antibody that targets cancer cells with a strong chemotherapy drug. For many patients with human epidermal growth factor receptor 2-positive (HER2+) breast cancers, ADCs such as trastuzumab deruxtecan (T-DXd) have dramatically improved outcomes.

STAT+: Pharmalittle: We’re reading about rising GLP-1 use, a psychedelic therapy for depression, and more​STAT+: Pharmalittle: We’re reading about rising GLP-1 use, a psychedelic therapy for depression, and more 

Rise and shine, everyone, another busy day is on the way. And it is getting off to a good start here on the Pharmalot campus, where we have cool breezes and clear blue skies greeting us today. Who could ask for anything more? Actually, we could — it is time to reheat the coffee kettle for Read More

Tirzepatide-Hormone Therapy Combo Tied to Weight Loss in Postmenopausal Women​Tirzepatide-Hormone Therapy Combo Tied to Weight Loss in Postmenopausal Women 

(MedPage Today) — ORLANDO — Postmenopausal women using hormone therapy (HT) saw significantly greater weight loss while taking the dual GIP/GLP-1 receptor agonist tirzepatide than their counterparts not using HT, according to a retrospective… ​ (MedPage Today) — ORLANDO — Postmenopausal women using hormone therapy (HT) saw significantly greater weight loss while taking the dual Read More

Weight-loss drugs like Ozempic may also curb drug and alcohol addiction​Weight-loss drugs like Ozempic may also curb drug and alcohol addiction 

GLP-1 drugs, originally developed for diabetes and obesity, may also curb addictive behaviors by acting on reward circuits in the brain. Early trials show reductions in alcohol intake, opioid seeking, and nicotine use. Though more research is needed, scientists believe these drugs could open a powerful new front in addiction therapy. ​GLP-1 drugs, originally developed Read More