New study elucidates obesity’s role in fueling breast cancer progressionNew study elucidates obesity’s role in fueling breast cancer progression
Obesity and cancer are two major health challenges of our time, yet the link between them remains only partially understood. New research now highlights a molecular chain of events in estrogen receptor-positive breast cancer, revealing how leptin, a hormone produced by fat cells, signals cancer cells to grow. This leads to increased activity of the enzyme stearoyl-CoA desaturase (SCD), which fuels the growth and motility of cancer cells.
Tracking RNA levels reveals new clues in triple-negative breast cancer progressionTracking RNA levels reveals new clues in triple-negative breast cancer progression
When researchers look for potential cancer therapy targets, they typically go after protein-coding genes that participate in disease progression. Disrupt them and negate whatever role they play in cancer’s development or spread. Researchers at Cold Spring Harbor Laboratory (CSHL) have also been working on another kind of target. They’re studying a long non-coding RNA called MALAT1. So far, it’s been linked to more than 20 different types of tumors.
Connecticut doctors are part of new cancer trials: The goal? ‘Eradicate all deaths from breast cancer’Connecticut doctors are part of new cancer trials: The goal? ‘Eradicate all deaths from breast cancer’
About 170,000 women in the United States are living with metastatic breast cancer—or cancer that has spread to other organs—and eventually leads to death.
Hims & Hers Weight Loss Shots: What You Need To Know About The GLP-1s And Compounded DrugsHims & Hers Weight Loss Shots: What You Need To Know About The GLP-1s And Compounded Drugs
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First it was Ozempic. Now the peptide gold rush is here — and it’s dangerousFirst it was Ozempic. Now the peptide gold rush is here — and it’s dangerous
Ozempic changed everything: Millions of Americans who have discovered the transformative power of one peptide are chasing their next fix Ozempic changed everything: Millions of Americans who have discovered the transformative power of one peptide are chasing their next fix
STAT+: Is the White House’s deal with pharma on GLP-1 drugs a game changer? STAT+: Is the White House’s deal with pharma on GLP-1 drugs a game changer?
President Trump last week hailed his deal with pharma companies to cut the price of blockbuster weight loss drugs as a major win for his administration and for increasing drug affordability. The question is how big of a difference the agreement will make for patients. The deal is expected to significantly expand access to GLP-1 Read More
Gordon Ramsay calls Ozempic restaurant menus ‘absolute bulls—‘ in profanity-filled rantGordon Ramsay calls Ozempic restaurant menus ‘absolute bulls—‘ in profanity-filled rant
Gordon Ramsay didn’t hold back when speaking out on whether he would alter his restaurants’ menus to cater to diners who are taking popular weight loss drugs including Ozempic and Mounjaro. During a recent interview with The Sunday Times, the 59-year-old celebrity chef was asked whether he would create special, smaller-portion menus for patrons using Read More
America’s obesity crisis meets the Ozempic boom as data reveals GLP-1 hot spotsAmerica’s obesity crisis meets the Ozempic boom as data reveals GLP-1 hot spots
With new agreements from President Donald Trump promising lower prices on popular weight-loss drugs, the use of GLP-1 medications such as Ozempic and Mounjaro could soon surge even higher — a trend already spreading unevenly across the U.S., with some states seeing greater uptick than others. Based on insurance claims data from Purple Lab, a Read More
Novel GLP-1 Drug on Attack Path Against Very High TriglyceridesNovel GLP-1 Drug on Attack Path Against Very High Triglycerides
(MedPage Today) — NEW ORLEANS — An investigational triple-receptor agonist made some headway in patients with severe hypertriglyceridemia, a phase II study showed. One Chinese cohort had triglycerides slashed from around 800 mg/dL at baseline… (MedPage Today) — NEW ORLEANS — An investigational triple-receptor agonist made some headway in patients with severe hypertriglyceridemia, a Read More
GLP-1 Use Prior to Pregnancy Tied to Lower Gestational Diabetes RiskGLP-1 Use Prior to Pregnancy Tied to Lower Gestational Diabetes Risk
(MedPage Today) — ATLANTA — Women who had been taking GLP-1 receptor agonist medications prior to becoming pregnant had a lower risk of gestational diabetes but not pre-eclampsia during pregnancy, according to a small retrospective cohort study… (MedPage Today) — ATLANTA — Women who had been taking GLP-1 receptor agonist medications prior to becoming Read More