Breakthrough GLP-1 implant promises major weight-loss benefits for pets​Breakthrough GLP-1 implant promises major weight-loss benefits for pets 

The world’s first GLP-1 weight loss treatment is being administered for pets on an experimental basis. The first cat was successfully dosed in the MEOW-1 study of OKV-119 – an investigational “ultra-long acting” GLP-1 implant, which, according to a press release, is being developed for weight management in cats. OKAVA Pharmaceuticals, the San Francisco-based manufacturer Read More

FDA Approves GLP-1 Pill for Cardiovascular Risk in Type 2 Diabetes​FDA Approves GLP-1 Pill for Cardiovascular Risk in Type 2 Diabetes 

The US Food and Drug Administration (FDA) recently approved Novo Nordisk’s oral semaglutide, marketed as Rybelsus, to reduce the risk of major adverse cardiac events in adults with type 2 diabetes who are at high risk of these conditions. ​The US Food and Drug Administration (FDA) recently approved Novo Nordisk’s oral semaglutide, marketed as Rybelsus, Read More

GLP-1 receptor agonists show little effect on obesity-related cancer risk​GLP-1 receptor agonists show little effect on obesity-related cancer risk 

1. In this systematic review and meta-analysis, use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) was not associated with a significant change in the risk of thyroid, pancreatic, breast, or kidney cancer. 2. Findings were consistent across subgroups, including by follow-up duration and among trials enrolling patients with type 2 diabetes, overweight or obesity, or both Read More

GLP-1 drugs have ‘little or no effect’ on risk of obesity-related cancers, study suggests​GLP-1 drugs have ‘little or no effect’ on risk of obesity-related cancers, study suggests 

Popular weight-loss drugs “probably have little or no effect” on a person’s risk of developing one of the 13 obesity-related cancers, new research suggests. ​Popular weight-loss drugs “probably have little or no effect” on a person’s risk of developing one of the 13 obesity-related cancers, new research suggests. 

GLP-1 receptor agonists likely have little or no effect on obesity-related cancer risk, research shows​GLP-1 receptor agonists likely have little or no effect on obesity-related cancer risk, research shows 

A systematic review and meta-analysis evaluated the risk for obesity-related cancer associated with glucagon-like peptide-1 receptor agonists (GLP-1RAs) in patients with type 2 diabetes (T2D) or overweight or obesity. ​A systematic review and meta-analysis evaluated the risk for obesity-related cancer associated with glucagon-like peptide-1 receptor agonists (GLP-1RAs) in patients with type 2 diabetes (T2D) or Read More

Her food cravings vanished on Mounjaro then roared back​Her food cravings vanished on Mounjaro then roared back 

Deep-brain recordings showed that Mounjaro and Zepbound briefly shut down the craving circuits linked to food noise in a patient with severe obesity. Her obsessive thoughts about food disappeared as the medication quieted the nucleus accumbens, the brain’s reward hub. ​Deep-brain recordings showed that Mounjaro and Zepbound briefly shut down the craving circuits linked to Read More