Estimates of breast cancer risk for pathogenic variants vary by family historyEstimates of breast cancer risk for pathogenic variants vary by family history

Population-based estimates of cumulative breast cancer risk for established pathogenic variants (PVs) vary by family history and potentially modifiable risk factors, according to a study published online Oct. 9 in JAMA Oncology.
Katie Thurston on Extreme Fatigue, Painful Sex, and Other Hidden Truths of Stage 4 Breast CancerKatie Thurston on Extreme Fatigue, Painful Sex, and Other Hidden Truths of Stage 4 Breast Cancer

The former ‘Bachelorette’ opens up to SELF and debunks common misconceptions.
Weight loss with GLP-1 analogs in diabetes benefits stroke recoveryWeight loss with GLP-1 analogs in diabetes benefits stroke recovery

Drugs targeting the glucagon-like peptide 1 receptor (GLP-1R) offer several positive effects for individuals with type 2 diabetes, including the lowering of blood glucose and the reduction of body weight and of cardiovascular risk. In a study in mice, researchers at KI SÖS and Södersjukhuset have shown that the specific weight-loss properties of these treatments Read More
Study links obesity-driven fatty acids to breast cancer, warns against high-fat diets like ketoStudy links obesity-driven fatty acids to breast cancer, warns against high-fat diets like keto

A team from Huntsman Cancer Institute at the University of Utah (the U) has found that triple-negative breast cancer is fueled by lipids and that these fatty acids are a key feature of obesity that promote tumor growth. Their research, conducted in preclinical mouse models, suggests that breast cancer patients and survivors with obesity could benefit from lipid-lowering therapies—and that they should avoid high-fat weight loss regimens like ketogenic diets.
Strong grip strength may protect against obesity-related complicationsStrong grip strength may protect against obesity-related complications

People with excess body fat who build and keep muscle may be less likely to develop obesity-induced heart, liver, or kidney damage or die early, according to a new study published in The Journal of Clinical Endocrinology & Metabolism.
GLP-1 drugs may delay alcohol’s effects in the bloodstreamGLP-1 drugs may delay alcohol’s effects in the bloodstream

There’s mounting evidence that popular drugs prescribed for diabetes management and weight loss—better known by trade names like Ozempic and Wegovy—could be effective in reducing alcohol use. There’s mounting evidence that popular drugs prescribed for diabetes management and weight loss—better known by trade names like Ozempic and Wegovy—could be effective in reducing alcohol use.
Medicare Decision on GLP-1s Soon; Inhaled Insulin Under Review for Kids; ‘Manopause’Medicare Decision on GLP-1s Soon; Inhaled Insulin Under Review for Kids; ‘Manopause’

(MedPage Today) — CMS Administrator Mehmet Oz, MD, MBA, said his agency will make an announcement on potential Medicare coverage of GLP-1 receptor agonists “very soon.” (CNBC) Preclinical studies “have consistently demonstrated the potential… (MedPage Today) — CMS Administrator Mehmet Oz, MD, MBA, said his agency will make an announcement on potential Medicare coverage Read More
Medicare Decision on GLP-1s Soon; Inhaled Insulin Under Review for Kids; ‘Manopause’Medicare Decision on GLP-1s Soon; Inhaled Insulin Under Review for Kids; ‘Manopause’
(MedPage Today) — CMS Administrator Mehmet Oz, MD, MBA, said his agency will make an announcement on potential Medicare coverage of GLP-1 receptor agonists “very soon.” (CNBC) Preclinical studies “have consistently demonstrated the potential… (MedPage Today) — CMS Administrator Mehmet Oz, MD, MBA, said his agency will make an announcement on potential Medicare coverage […]
American Cancer Society Research Grantee Improving Breast Cancer Screening & Care ExperienceAmerican Cancer Society Research Grantee Improving Breast Cancer Screening & Care Experience

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GLP-1 Drugs Associated With Lower Overall Cancer RiskGLP-1 Drugs Associated With Lower Overall Cancer Risk
Obesity is a risk factor for several forms of cancer that comprise 40% of annual cancer diagnoses in the US. New findings published in JAMA Oncology suggest that glucagon-like peptide-1 (GLP-1) receptor agonists may help protect against some of these cancer types. Obesity is a risk factor for several forms of cancer that comprise 40% Read More