Clinical Highlights From ESC 2025—GLP-1 Drugs in Heart Failure and MoreClinical Highlights From ESC 2025—GLP-1 Drugs in Heart Failure and More
This Medical News article is an interview with Felix Mahfoud, MD, chair of the Department of Cardiology at University Hospital Basel, about clinical highlights from the European Society of Cardiology Congress held recently in Madrid. This Medical News article is an interview with Felix Mahfoud, MD, chair of the Department of Cardiology at University Hospital Read More
GLP-1 Drugs May Manage Weight Recurrence After Bariatric SurgeryGLP-1 Drugs May Manage Weight Recurrence After Bariatric Surgery
Glucagon-like peptide-1 (GLP-1) receptor agonists may support weight management in patients following bariatric surgery. A study suggests that GLP-1 drug use is particularly common among those with less postsurgical weight loss. Glucagon-like peptide-1 (GLP-1) receptor agonists may support weight management in patients following bariatric surgery. A study suggests that GLP-1 drug use is particularly common Read More
Obesity-related cancer rising among both younger and older adults worldwide, study findsObesity-related cancer rising among both younger and older adults worldwide, study finds

A surveillance study compared international cancer incidence trends of 13 cancer types in younger and older adults.
Mortality down with GLP-1 receptor agonist use in T2D, especially in those with OSAMortality down with GLP-1 receptor agonist use in T2D, especially in those with OSA

Patients with type 2 diabetes mellitus (T2DM) prescribed glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have significantly lower one-year mortality, especially those also diagnosed with obstructive sleep apnea (OSA), according to a study presented at CHEST 2025, the annual meeting of the American College of Chest Physicians, held from Oct. 19 to 22 in Chicago. Patients Read More
FDA Approves GLP-1 Pill for Primary, Secondary Cardiovascular ProtectionFDA Approves GLP-1 Pill for Primary, Secondary Cardiovascular Protection

(MedPage Today) — The FDA approved oral semaglutide (Rybelsus) to prevent major adverse cardiovascular events (MACE) in high-risk patients with diabetes, whether or not they’ve had such an event already, Novo Nordisk announced. Semaglutide 7… (MedPage Today) — The FDA approved oral semaglutide (Rybelsus) to prevent major adverse cardiovascular events (MACE) in high-risk patients Read More
De-Escalating Bone-Modifying Therapy Safe, Effective in Metastatic Breast CancerDe-Escalating Bone-Modifying Therapy Safe, Effective in Metastatic Breast Cancer

(MedPage Today) — BERLIN — Administering bone-modifying agents (BMAs) every 24 weeks after long-term use was a safe and effective strategy for patients with bone metastases from breast cancer, and also appeared to be safe in prostate cancer…
Breastfeeding causes a surge in immune cells that could prevent cancerBreastfeeding causes a surge in immune cells that could prevent cancer

Breastfeeding seems to cause specialised immune cells to flood into the breasts and stay there for years or even decades, reducing the risk of cancer
New generation of antibody-drug conjugates shows promise in early-stage HER2-positive breast cancerNew generation of antibody-drug conjugates shows promise in early-stage HER2-positive breast cancer

In a landmark moment at the ESMO Congress 2025, pivotal studies have unveiled compelling evidence that a new class of anti-cancer agents—antibody-drug conjugates (ADCs)—can dramatically improve outcomes for patients with early-stage HER2-positive breast cancer.
Protective immune cells in breastfeeding women identified as guard against breast cancer, new research findsProtective immune cells in breastfeeding women identified as guard against breast cancer, new research finds

Patients who had more cells had better outcomes, particularly for aggressive types such as triple-negative breast cancerIn the 18th century, physicians noticed nuns had some of the highest rates of breast cancer. It was one of the earliest clues that led scientists to suspect that child-bearing and breastfeeding could protect against the disease.Modern data has confirmed the centuries-old observation but the biological reasons behind it have remained unclear. Explanations have often focused on pregnancy-related hormonal changes, but research published Tuesday in Nature has found breastfeeding provides long-lasting immune protection. Continue reading…
ADC improves outcomes in advanced triple-negative breast cancer patients ineligible for immune checkpoint inhibitorsADC improves outcomes in advanced triple-negative breast cancer patients ineligible for immune checkpoint inhibitors

Patients with an aggressive form of breast cancer who are not candidates for immune checkpoint inhibitor therapy showed significantly improved progression-free survival when treated with the antibody drug conjugate sacituzumab govitecan compared to standard chemotherapy.