Oral drug combination extends progression-free survival in advanced ER-positive breast cancerOral drug combination extends progression-free survival in advanced ER-positive breast cancer
Patients with estrogen-receptor-positive HER-2-negative advanced breast cancer showed significantly improved progression-free survival when treated with an oral combination regimen that includes giredestrant, a novel, next-generation selective estrogen receptor degrader and full antagonist, compared to a standard combination approach. These findings, from the phase 3 evERA Breast Cancer study, are presented today by Dr. Erica Mayer of Dana-Farber Cancer Institute at the annual meeting of the European Society for Medical Oncology (ESMO) in Berlin, Germany.
Chemical linked to low sperm count, obesity and cancer found in dummies, tests findChemical linked to low sperm count, obesity and cancer found in dummies, tests find
BPA, a synthetic chemical used in production of plastics, found in baby products made by three big European brandsA chemical linked to impaired sexual development, obesity and cancer has been found in baby dummies manufactured by three big European brands.Dummies made by the Dutch multinational Philips, the Swiss oral health specialists Curaprox and the French toy brand Sophie la Girafe were found to contain bisphenol A (BPA), according to laboratory testing by dTest, a Czech consumer organisation. Philips said they had carried out subsequent testing and found no BPA, while Sophie la Girafe said the amount found was insignificant. Continue reading…
Can Ozempic help you cut back on alcohol? Researchers think soCan Ozempic help you cut back on alcohol? Researchers think so
Semaglutide, tirzepatide, and other GLP-1 drugs appear to slow alcohol absorption and blunt its intoxicating effects, according to new research. The study found participants on these medications felt less drunk despite consuming the same amount of alcohol. This could point to a safer, faster-acting way to help people reduce drinking—distinct from traditional treatments that target Read More
Trump says Ozempic will get much cheaper. Novo Nordisk and Eli Lilly shares tumbleTrump says Ozempic will get much cheaper. Novo Nordisk and Eli Lilly shares tumble
Trump’s comments on Ozempic “signal aggressive posturing” in drug price negotiations, an analyst said Trump’s comments on Ozempic “signal aggressive posturing” in drug price negotiations, an analyst said
Estimates of breast cancer risk for pathogenic variants vary by family historyEstimates of breast cancer risk for pathogenic variants vary by family history
Population-based estimates of cumulative breast cancer risk for established pathogenic variants (PVs) vary by family history and potentially modifiable risk factors, according to a study published online Oct. 9 in JAMA Oncology.
Katie Thurston on Extreme Fatigue, Painful Sex, and Other Hidden Truths of Stage 4 Breast CancerKatie Thurston on Extreme Fatigue, Painful Sex, and Other Hidden Truths of Stage 4 Breast Cancer
The former ‘Bachelorette’ opens up to SELF and debunks common misconceptions.
Weight loss with GLP-1 analogs in diabetes benefits stroke recoveryWeight loss with GLP-1 analogs in diabetes benefits stroke recovery
Drugs targeting the glucagon-like peptide 1 receptor (GLP-1R) offer several positive effects for individuals with type 2 diabetes, including the lowering of blood glucose and the reduction of body weight and of cardiovascular risk. In a study in mice, researchers at KI SÖS and Södersjukhuset have shown that the specific weight-loss properties of these treatments Read More
Study links obesity-driven fatty acids to breast cancer, warns against high-fat diets like ketoStudy links obesity-driven fatty acids to breast cancer, warns against high-fat diets like keto
A team from Huntsman Cancer Institute at the University of Utah (the U) has found that triple-negative breast cancer is fueled by lipids and that these fatty acids are a key feature of obesity that promote tumor growth. Their research, conducted in preclinical mouse models, suggests that breast cancer patients and survivors with obesity could benefit from lipid-lowering therapies—and that they should avoid high-fat weight loss regimens like ketogenic diets.
Strong grip strength may protect against obesity-related complicationsStrong grip strength may protect against obesity-related complications
People with excess body fat who build and keep muscle may be less likely to develop obesity-induced heart, liver, or kidney damage or die early, according to a new study published in The Journal of Clinical Endocrinology & Metabolism.
GLP-1 drugs may delay alcohol’s effects in the bloodstreamGLP-1 drugs may delay alcohol’s effects in the bloodstream
There’s mounting evidence that popular drugs prescribed for diabetes management and weight loss—better known by trade names like Ozempic and Wegovy—could be effective in reducing alcohol use. There’s mounting evidence that popular drugs prescribed for diabetes management and weight loss—better known by trade names like Ozempic and Wegovy—could be effective in reducing alcohol use.