Overcoming CDK4/6 Inhibitor Resistance in HR-Positive/HER2-Negative Breast CancerOvercoming CDK4/6 Inhibitor Resistance in HR-Positive/HER2-Negative Breast Cancer
(MedPage Today) — In the decade since palbociclib (Ibrance) received FDA approval, results from multiple clinical trials have provided a strong evidence base to make cyclin-dependent kinase (CDK)4/6 inhibitors, in combination with endocrine therapy…
New Wegovy pill offers needle-free weight loss — but may not work for everyoneNew Wegovy pill offers needle-free weight loss — but may not work for everyone
The first oral GLP-1 medication for weight loss has been approved for use in the U.S. The Wegovy pill, from drugmaker Novo Nordisk, was cleared by the Food and Drug Administration to reduce excess body weight, maintain long-term weight reduction and lower the risk of major cardiovascular events. Approval of the once-daily 25mg semaglutide pill Read More
Chipotle to offer GLP-1 menu options for customersChipotle to offer GLP-1 menu options for customers
Chipotle to offer GLP-1 menu options for customers Chipotle to offer GLP-1 menu options for customers
Wegovy Pill: Answers to Your Top QuestionsWegovy Pill: Answers to Your Top Questions
While injectable medications have dominated the weight loss space for years, most people aren’t exactly pumped to stick themselves with a needle, so pills like the one from Wegovy could be game-changers. While injectable medications have dominated the weight loss space for years, most people aren’t exactly pumped to stick themselves with a needle, so Read More
Night shifts aren’t just tiring, they can be deadly: Disrupted sleep cycles linked to aggressive breast cancerNight shifts aren’t just tiring, they can be deadly: Disrupted sleep cycles linked to aggressive breast cancer
Working the night shift, frequently flying across time zones or keeping an irregular sleep schedule does more than just leave us exhausted; it can fuel the risk of aggressive breast cancer. Exactly how and why this happens has remained a mystery, until now.
Prediabetes Reversal Benefits; Many Seniors Quit GLP-1s in a Year; Testosterone FadsPrediabetes Reversal Benefits; Many Seniors Quit GLP-1s in a Year; Testosterone Fads
(MedPage Today) — Achieving prediabetes remission was tied to a decades-long benefit — a reduction in risk of cardiovascular death or hospitalization for heart failure — in a post-hoc analysis of two landmark diabetes prevention trials… (MedPage Today) — Achieving prediabetes remission was tied to a decades-long benefit — a reduction in risk of Read More
GLP-1s Quieted My Migraines, But Awakened Something DarkerGLP-1s Quieted My Migraines, But Awakened Something Darker
I’d sworn I was done chasing smallness as a virtue. How am I back here again? I’d sworn I was done chasing smallness as a virtue. How am I back here again?
FDA approves Wegovy pill, the first prescription pill for weight lossFDA approves Wegovy pill, the first prescription pill for weight loss
The FDA has approved the pill version of the weight loss drug Wegovy, the first oral medication of its kind. The new pills are expected to be available in a few weeks. Chief medical correspondent Dr. Jon LaPook has more. The FDA has approved the pill version of the weight loss drug Wegovy, the first Read More
STAT+: We’re reading about the first approved GLP-1 pill, deal-hungry Ipsen, and moreSTAT+: We’re reading about the first approved GLP-1 pill, deal-hungry Ipsen, and more
Good morning, Pharmalittle readers. This is Allison DeAngelis, filling in for Mr. Pharmalot. Today’s newsletter is brought to you by the dark roast Keurig pods I brought with me on my holiday travels. I was appalled to discover during my Thanksgiving visit that the family member who was hosting only had decaf pods available. What Read More
FDA Approves Wegovy Weight-Loss PillFDA Approves Wegovy Weight-Loss Pill
(MedPage Today) — The FDA approved a pill version of the GLP-1 receptor agonist semaglutide (Wegovy), making it the first oral GLP-1 agent indicated for weight loss, Novo Nordisk announced on Monday. The once-daily 25 mg pill is approved to lower… (MedPage Today) — The FDA approved a pill version of the GLP-1 receptor Read More