Where you live may be fueling aggressive breast cancer​Where you live may be fueling aggressive breast cancer 

New research shows that women living near Superfund sites are more likely to develop aggressive and metastatic breast cancers. The studies found higher risks for hard-to-treat subtypes like triple-negative breast cancer, especially in areas with greater air pollution. Scientists also discovered molecular tumor changes linked to neighborhood deprivation. The findings point to environmental exposure and social conditions as key factors shaping cancer outcomes.

What to know as first FDA-approved GLP-1 pill for weight loss heads for pharmacies​What to know as first FDA-approved GLP-1 pill for weight loss heads for pharmacies 

The FDA has approved the first GLP-1 pill for weight loss and it’s expected in pharmacies in the coming weeks. Dr. Holly Lofton, director of the Medical Weight Management Program at NYU Langone, joins CBS News to discuss. ​The FDA has approved the first GLP-1 pill for weight loss and it’s expected in pharmacies in Read More

75% of Adults Have Obesity; Gestational Diabetes Rates Rising; Oprah Praises GLP-1s​75% of Adults Have Obesity; Gestational Diabetes Rates Rising; Oprah Praises GLP-1s 

(MedPage Today) — Over 75% of U.S. adults have obesity under a global Lancet Commission’s new definition of obesity, which includes three anthropometric measures along with body mass index. (JAMA Network Open) Officials are hoping access to GLP… ​ (MedPage Today) — Over 75% of U.S. adults have obesity under a global Lancet Commission’s new Read More

Tirzepatide noninferior to dulaglutide for CV outcomes in type 2 diabetes​Tirzepatide noninferior to dulaglutide for CV outcomes in type 2 diabetes 

Tirzepatide is noninferior to dulaglutide with respect to a composite of death from cardiovascular (CV) causes, myocardial infarction, or stroke among patients with type 2 diabetes and atherosclerotic CV disease, according to a study published in the Dec. 18/25 issue of the New England Journal of Medicine. ​Tirzepatide is noninferior to dulaglutide with respect to Read More

How pregnancy and breastfeeding enhance local immunity that cancer-proof the breast​How pregnancy and breastfeeding enhance local immunity that cancer-proof the breast 

For centuries, physicians observed that nuns, who are celibate, had much higher rates of breast cancer, leading to the theory that pregnancy, childbirth, and breastfeeding might be associated with lower breast cancer risk. Numerous epidemiological studies have since supported this, finding that women with more children and breastfed tend to have lower rates of breast cancer and other reproductive issues.

Effect of adjuvant carboplatin intensified chemotherapy versus standard chemotherapy on survival in women with high risk, early stage, triple negative breast cancer (CITRINE): randomised, open label phase 3 trial​Effect of adjuvant carboplatin intensified chemotherapy versus standard chemotherapy on survival in women with high risk, early stage, triple negative breast cancer (CITRINE): randomised, open label phase 3 trial 

1. Among patients with high-risk, early-stage triple-negative breast cancer, the addition of carboplatin to a standard anthracycline/taxane adjuvant chemotherapy regimen significantly improved survival outcomes with a reduction in early recurrence risk.  Evidence Rating Level: 1 (Excellent) Among the classical subtypes of breast cancer, triple-negative breast cancer is an aggressive disease with higher early recurrence than
The post Effect of adjuvant carboplatin intensified chemotherapy versus standard chemotherapy on survival in women with high risk, early stage, triple negative breast cancer (CITRINE): randomised, open label phase 3 trial first appeared on 2 Minute Medicine. Source: 2 Minute Medicine

STAT+: With the Wegovy pill, Novo Nordisk undercuts Eli Lilly in direct-to-consumer market​STAT+: With the Wegovy pill, Novo Nordisk undercuts Eli Lilly in direct-to-consumer market 

Novo Nordisk plans to sell its newly approved obesity pill directly to patients at a lower price than a competing medicine from Eli Lilly, as the Danish drugmaker tries to seize market share among consumers paying cash for blockbuster GLP-1 therapies. Novo will sell the highest doses of its Wegovy pill, cleared last week, at Read More

GLP-1 Agents Tied to Less Risk of Asthma Exacerbations in Teens With Obesity​GLP-1 Agents Tied to Less Risk of Asthma Exacerbations in Teens With Obesity 

(MedPage Today) — Adolescents with overweight or obesity and asthma had a lower risk of asthma exacerbations after starting a GLP-1 receptor agonist, a retrospective cohort study found. Among 1,070 patients ages 12 to 18, 5.4% of those taking… ​ (MedPage Today) — Adolescents with overweight or obesity and asthma had a lower risk of Read More