Denosumab discontinuation in non-metastatic breast cancer treated with AI raises vertebral fracture risk​Denosumab discontinuation in non-metastatic breast cancer treated with AI raises vertebral fracture risk 

Aromatase inhibitors (AIs) are a cornerstone of adjuvant therapy for hormone receptor–positive breast cancer, significantly reducing recurrence and mortality. However, by suppressing estrogen production, AIs accelerate bone loss and increase fracture risk. To counter this, antiresorptive therapies such as denosumab or bisphosphonates are widely recommended.

GLP-1 Receptor Agonists Plus Progestins and Endometrial Cancer Risk​GLP-1 Receptor Agonists Plus Progestins and Endometrial Cancer Risk 

This cohort study compares the associations of glucagon-like peptide-1 (GLP-1) receptor agonists and of progestins with risk of endometrial cancer among US women with endometrial hyperplasia or other benign uterine pathologies. ​This cohort study compares the associations of glucagon-like peptide-1 (GLP-1) receptor agonists and of progestins with risk of endometrial cancer among US women with Read More

STAT+: Novo Nordisk sues Hims & Hers for infringing on a key Wegovy patent​STAT+: Novo Nordisk sues Hims & Hers for infringing on a key Wegovy patent 

Novo Nordisk has filed a lawsuit accusing Hims & Hers of infringing on a key patent for its widely sold Wegovy weight loss treatment, a new legal tactic by the drugmaker as it tries to thwart compounded versions of its big-selling medicine. Specifically, Novo Nordisk claims the telehealth platform infringed on the patent for semaglutide, Read More

STAT+: HHS asks Justice Department to probe Hims & Hers over its cheaper compounded version of Wegovy​STAT+: HHS asks Justice Department to probe Hims & Hers over its cheaper compounded version of Wegovy 

The Department of Health and Human Services asked the Department of Justice to investigate Hims & Hers for potentially violating federal law over its plan to make a compounded version of a low-cost weight loss pill widely available on its telehealth platform, according to a social media post by HHS general counsel Mike Stuart. The Read More