Challenges for a crucial sickle cell treatment and the latest outlook for GLP-1s​Challenges for a crucial sickle cell treatment and the latest outlook for GLP-1s 

On this week’s episode of The Readout LOUD: two starkly different financial outlooks from Novo Nordisk and Eli Lilly, a psychedelics drug from Compass Pathways encountered a roadblock with the Trump White House, and a closer look at why manufacturing problems have slowed the rollout of a crucial sickle cell treatment.  It’s our pre-Super Bowl show, Read More

STAT+: Novo Nordisk accuses Hims & Hers of ‘illegal mass compounding’ over a cheaper version of Wegovy pill​STAT+: Novo Nordisk accuses Hims & Hers of ‘illegal mass compounding’ over a cheaper version of Wegovy pill 

In an unexpected move, Hims & Hers is making available a cheaper, compounded version of the Wegovy weight loss pill sold by Novo Nordisk, prompting the drugmaker to accuse the telehealth platform of “illegal mass compounding.” In announcing its move, Hims & Hers said it would make compounded copies of Wegovy available on its platform Read More

Hims & Hers Launches Copy of Wegovy Pill, Prompting Legal Threats​Hims & Hers Launches Copy of Wegovy Pill, Prompting Legal Threats 

(MedPage Today) — Telehealth company Hims & Hers said Thursday it will launch a cheaper, off-brand version of the weight-loss pill semaglutide (Wegovy), just weeks after drugmaker Novo Nordisk launched its highly anticipated reformulation… ​ (MedPage Today) — Telehealth company Hims & Hers said Thursday it will launch a cheaper, off-brand version of the weight-loss Read More

A reliable atlas of cell types found in breast cancers​A reliable atlas of cell types found in breast cancers 

Breast cancer (BC) is the most common cancer and the second leading cause of cancer death in women. It is a highly variable disease, defined as a malignancy of the epithelial ducts in breast tissue. Characterizing the vast heterogeneity within BC cells and their surrounding tumor microenvironment is crucial because this diversity is the primary reason for treatment resistance, disease progression and poor patient prognosis.

Semaglutide improves cardiovascular health but price reductions are needed to make it cost-effective, study finds​Semaglutide improves cardiovascular health but price reductions are needed to make it cost-effective, study finds 

Semaglutide, the active ingredient in the weight-loss medications Ozempic and Wegovy, offers substantial cardiovascular benefits for selected patients without diabetes who have established heart disease, but further price reductions are needed to make the therapy good value for money, according to a new analysis from researchers at Beth Israel Deaconess Medical Center (BIDMC). ​Semaglutide, the Read More

GLP-1 ‘Agonorexia’; Psychotic Disorders Rising in Young People; Pink Noise Pitfalls​GLP-1 ‘Agonorexia’; Psychotic Disorders Rising in Young People; Pink Noise Pitfalls 

(MedPage Today) — Clinicians are seeing more cases of “agonorexia,” when use of GLP-1 receptor agonists turns into disordered eating. (New York Post) Colorado could become the first state to use ibogaine, a plant-based psychoactive compound… ​ (MedPage Today) — Clinicians are seeing more cases of “agonorexia,” when use of GLP-1 receptor agonists turns into Read More