A reliable atlas of cell types found in breast cancers​A reliable atlas of cell types found in breast cancers 

Breast cancer (BC) is the most common cancer and the second leading cause of cancer death in women. It is a highly variable disease, defined as a malignancy of the epithelial ducts in breast tissue. Characterizing the vast heterogeneity within BC cells and their surrounding tumor microenvironment is crucial because this diversity is the primary reason for treatment resistance, disease progression and poor patient prognosis.

Semaglutide improves cardiovascular health but price reductions are needed to make it cost-effective, study finds​Semaglutide improves cardiovascular health but price reductions are needed to make it cost-effective, study finds 

Semaglutide, the active ingredient in the weight-loss medications Ozempic and Wegovy, offers substantial cardiovascular benefits for selected patients without diabetes who have established heart disease, but further price reductions are needed to make the therapy good value for money, according to a new analysis from researchers at Beth Israel Deaconess Medical Center (BIDMC). ​Semaglutide, the Read More

GLP-1 ‘Agonorexia’; Psychotic Disorders Rising in Young People; Pink Noise Pitfalls​GLP-1 ‘Agonorexia’; Psychotic Disorders Rising in Young People; Pink Noise Pitfalls 

(MedPage Today) — Clinicians are seeing more cases of “agonorexia,” when use of GLP-1 receptor agonists turns into disordered eating. (New York Post) Colorado could become the first state to use ibogaine, a plant-based psychoactive compound… ​ (MedPage Today) — Clinicians are seeing more cases of “agonorexia,” when use of GLP-1 receptor agonists turns into Read More

GLP-1 obesity drugs can complicate life for people with disordered eating​GLP-1 obesity drugs can complicate life for people with disordered eating 

Doctors, patients and researchers are at the very beginning of understanding how the new class of obesity drugs interact with eating disorders. (Image credit: Edwin J. Torres for NPR) ​ Doctors, patients and researchers are at the very beginning of understanding how the new class of obesity drugs interact with eating disorders. (Image credit: Edwin Read More

RNA molecule discovery could lead to potential new breast cancer therapy​RNA molecule discovery could lead to potential new breast cancer therapy 

QIMR Berghofer scientists have discovered a cancer-fighting RNA molecule that could hold the key to a new way of treating the most common form of breast cancer. The team are developing their findings into a potential RNA-based therapy for hormone receptor-positive (HR+) breast cancer, offering hope to women with advanced disease who are no longer responding to existing drugs.

More GLP-1 Drug Lawsuits; Military’s Rising Obesity Rates; Male Birth Control Soon?​More GLP-1 Drug Lawsuits; Military’s Rising Obesity Rates; Male Birth Control Soon? 

(MedPage Today) — More lawsuits are alleging that patients are not being sufficiently warned of certain severe injuries associated with GLP-1 receptor agonists. (USA Today) Meanwhile, the U.K.’s Medicines and Healthcare Products Regulatory Agency… ​ (MedPage Today) — More lawsuits are alleging that patients are not being sufficiently warned of certain severe injuries associated with Read More

Rethinking weight loss in the Ozempic era: Researchers urge a more holistic view​Rethinking weight loss in the Ozempic era: Researchers urge a more holistic view 

In the world of obesity research, the arrival of GLP-1 drugs like Ozempic feels seismic. At a recent conference, Martin Binks, a leader in obesity research, found himself marveling with a colleague: “Can you believe we finally reached this moment, that we lived long enough to see this?” ​In the world of obesity research, the Read More