A reliable atlas of cell types found in breast cancersA reliable atlas of cell types found in breast cancers

Breast cancer (BC) is the most common cancer and the second leading cause of cancer death in women. It is a highly variable disease, defined as a malignancy of the epithelial ducts in breast tissue. Characterizing the vast heterogeneity within BC cells and their surrounding tumor microenvironment is crucial because this diversity is the primary reason for treatment resistance, disease progression and poor patient prognosis.
Semaglutide improves cardiovascular health but price reductions are needed to make it cost-effective, study findsSemaglutide improves cardiovascular health but price reductions are needed to make it cost-effective, study finds

Semaglutide, the active ingredient in the weight-loss medications Ozempic and Wegovy, offers substantial cardiovascular benefits for selected patients without diabetes who have established heart disease, but further price reductions are needed to make the therapy good value for money, according to a new analysis from researchers at Beth Israel Deaconess Medical Center (BIDMC). Semaglutide, the Read More
GLP-1 ‘Agonorexia’; Psychotic Disorders Rising in Young People; Pink Noise PitfallsGLP-1 ‘Agonorexia’; Psychotic Disorders Rising in Young People; Pink Noise Pitfalls

(MedPage Today) — Clinicians are seeing more cases of “agonorexia,” when use of GLP-1 receptor agonists turns into disordered eating. (New York Post) Colorado could become the first state to use ibogaine, a plant-based psychoactive compound… (MedPage Today) — Clinicians are seeing more cases of “agonorexia,” when use of GLP-1 receptor agonists turns into Read More
Wegovy pill in high demand in weeks since launch, Novo Nordisk saysWegovy pill in high demand in weeks since launch, Novo Nordisk says

Novo Nordisk said Wednesday that demand for its Wegovy pill got off to a strong start after it launched in the U.S. in early January Novo Nordisk said Wednesday that demand for its Wegovy pill got off to a strong start after it launched in the U.S. in early January
The overlooked nutrition risk of Ozempic and WegovyThe overlooked nutrition risk of Ozempic and Wegovy

Popular weight-loss drugs like Ozempic and Wegovy can dramatically curb appetite, but experts warn many users are flying blind when it comes to nutrition. New research suggests people taking these medications may not be getting enough guidance on protein, vitamins, and overall diet quality, increasing the risk of muscle loss and nutrient deficiencies. Popular weight-loss Read More
GLP-1 obesity drugs can complicate life for people with disordered eatingGLP-1 obesity drugs can complicate life for people with disordered eating
Doctors, patients and researchers are at the very beginning of understanding how the new class of obesity drugs interact with eating disorders. (Image credit: Edwin J. Torres for NPR) Doctors, patients and researchers are at the very beginning of understanding how the new class of obesity drugs interact with eating disorders. (Image credit: Edwin Read More
GLP-1 obesity drugs can complicate life for people with disordered eatingGLP-1 obesity drugs can complicate life for people with disordered eating
Doctors, patients and researchers are at the very beginning of understanding how the new weight loss medicines interact with eating disorders. Doctors, patients and researchers are at the very beginning of understanding how the new weight loss medicines interact with eating disorders.
RNA molecule discovery could lead to potential new breast cancer therapyRNA molecule discovery could lead to potential new breast cancer therapy

QIMR Berghofer scientists have discovered a cancer-fighting RNA molecule that could hold the key to a new way of treating the most common form of breast cancer. The team are developing their findings into a potential RNA-based therapy for hormone receptor-positive (HR+) breast cancer, offering hope to women with advanced disease who are no longer responding to existing drugs.
More GLP-1 Drug Lawsuits; Military’s Rising Obesity Rates; Male Birth Control Soon?More GLP-1 Drug Lawsuits; Military’s Rising Obesity Rates; Male Birth Control Soon?

(MedPage Today) — More lawsuits are alleging that patients are not being sufficiently warned of certain severe injuries associated with GLP-1 receptor agonists. (USA Today) Meanwhile, the U.K.’s Medicines and Healthcare Products Regulatory Agency… (MedPage Today) — More lawsuits are alleging that patients are not being sufficiently warned of certain severe injuries associated with Read More
Rethinking weight loss in the Ozempic era: Researchers urge a more holistic viewRethinking weight loss in the Ozempic era: Researchers urge a more holistic view

In the world of obesity research, the arrival of GLP-1 drugs like Ozempic feels seismic. At a recent conference, Martin Binks, a leader in obesity research, found himself marveling with a colleague: “Can you believe we finally reached this moment, that we lived long enough to see this?” In the world of obesity research, the Read More