STAT+: As China’s drug industry races ahead, its GLP-1 race is accelerating too​STAT+: As China’s drug industry races ahead, its GLP-1 race is accelerating too 

For American and European drugmakers, the story of China today is one of a fast-developing market — one producing not only “me too” therapies but increasingly novel medications as well. And to understand what these shifts might mean for global pharmaceutical companies, look no further than the market for GLP-1 drugs, in particular. Earlier this Read More

Researchers identify key mechanism driving progression of fatty liver disease to cancer​Researchers identify key mechanism driving progression of fatty liver disease to cancer 

According to recent reports from the Korean government, the incidence of alcoholic liver disease—previously the leading indication for liver transplantation—has been decreasing. This trend initially raised expectations that the medical burden of liver transplantation and liver-related mortality would decline. However, the current reality does not reflect this expectation. In addition, fatty liver disease is also increasing steadily due to modern lifestyle factors, and projections indicate that the demand for liver transplantation will continue to rise, with fatty liver-related cases increasingly replacing those caused by alcoholic liver disease.

Bariatric surgery programs face upheaval amid growing GLP-1 use for weight loss​Bariatric surgery programs face upheaval amid growing GLP-1 use for weight loss 

At Roxborough Memorial Hospital in Philadelphia, surgeon Piotr Krecioch has his hands full launching a program offering surgical interventions to treat obesity. One in three Philadelphians are living with obesity, putting them at higher risk of chronic conditions like diabetes and heart disease, but these days fewer are seeking the bariatric surgical procedures long considered Read More

How bacteria may promote breast cancer​How bacteria may promote breast cancer 

Researchers at the Johns Hopkins Kimmel Cancer Center have discovered how certain pathogenic bacteria in gut and breast tissue can promote breast cancer development and progression by hijacking a key metabolic enzyme known as spermine oxidase (SMOX). In a study led by Dipali Sharma, Ph.D., professor of oncology, investigators found that exposure to pathogenic bacteria such as Bacteroides fragilis, Fusobacterium nucleatum, and Escherichia coli significantly increased SMOX activity, leading to DNA damage, tumor growth, and metastasis in laboratory and animal models of breast cancer.

US teen who pushed for her father’s release from ICE custody dies of cancer​US teen who pushed for her father’s release from ICE custody dies of cancer 

Ofelia Torres, 16, spotlighted her dad Ruben’s illegal detention last fall during Trump’s crackdown in ChicagoA Chicago teenager, whose father was detained by immigration authorities while she navigated cancer, died on Friday, a family spokesperson said.Ofelia Torres, a 16-year-old in Chicago, had been undergoing treatment for an aggressive and rare form of cancer since late 2024. As she and her family struggled with the medical procedures, her father, Ruben Torres Maldonado, was detained by immigration authorities while at a Home Depot in October, leading to a contentious and public case that highlighted the human effects of the Trump administration’s aggressive immigration crackdown. Continue reading…

Combining GLP-1 drugs with hormones may lower uterine cancer risk​Combining GLP-1 drugs with hormones may lower uterine cancer risk 

Adding GLP-1 medications like Ozempic to progestin therapy could cut the risk of developing endometrial cancer. A retrospective study published in the journal JAMA Network Open found that women using this combination had a much lower risk of developing the disease than those on progestins alone. ​Adding GLP-1 medications like Ozempic to progestin therapy could Read More

FDA Leader Accused of Sexual Harassment; RFK Jr.’s Toilet Comment; GLP-1s and Scurvy​FDA Leader Accused of Sexual Harassment; RFK Jr.’s Toilet Comment; GLP-1s and Scurvy 

(MedPage Today) — Note that some links may require registration or subscription. FDA vaccine chief Vinay Prasad, MD, MPH, who made the controversial decision to refuse to review Moderna’s mRNA flu vaccine, has been accused of sexual harassment… ​ (MedPage Today) — Note that some links may require registration or subscription. FDA vaccine chief Vinay Read More