Study finds tirzepatide cuts alcohol intake by more than half in rodents​Study finds tirzepatide cuts alcohol intake by more than half in rodents 

For the first time, researchers show that tirzepatide—the active ingredient in the diabetes and weight-loss drug Mounjaro—reduces alcohol intake as well as relapse-like behaviors in rats and mice. The findings are considered relevant in the search for new treatments for alcohol use disorder. Researchers at the University of Gothenburg have previously demonstrated that semaglutide, found Read More

What’s next for GLP-1s?​What’s next for GLP-1s? 

Now that GLP-1 drugs have revolutionized how millions of Americans treat obesity and Type 2 diabetes, scientists are exploring the benefits of using the drugs for a host of other chronic diseases—many with few treatment options—such as heart failure, chronic liver disease, obstructive sleep apnea, and even substance use disorders. ​Now that GLP-1 drugs have Read More

Household cat could hold the key to understanding breast cancer​Household cat could hold the key to understanding breast cancer 

The first study of multiple cancer types in cats has identified genetic changes that could help treat the condition in humans and animals. By analyzing different types of tumors from almost 500 pet cats across five countries, experts at the Wellcome Sanger Institute, the Ontario Veterinary College in Canada, the University of Bern, and their collaborators, discovered the genetic changes that drive cancer formation in cats and found similarities between these and ones seen in humans.

Gordon Ramsay slams ‘stupid’ Ozempic-inspired restaurant menu trend​Gordon Ramsay slams ‘stupid’ Ozempic-inspired restaurant menu trend 

As Ozempic and Mounjaro reshape eating habits, some restaurants are adapting — and Gordon Ramsay isn’t impressed. The celebrity chef and star of Fox’s “Next Level Chef” said he thinks the new trend of GLP-1-inspired menus at restaurants is “stupid.” “If I ever hear that word again, the ‘Mounjaro menu,’ I will [expletive] flip my Read More

Opinion: My biggest GLP-1 ethical problem: patients who don’t want to stop​Opinion: My biggest GLP-1 ethical problem: patients who don’t want to stop 

It makes my head spin to think about how much GLP-1s have changed the medical weight management landscape in such a short time. In 2023, I wrote for STAT about GLP-1 shortages leading to treatment delays, interruptions, and difficult decisions about who “deserved” to get these precious medications. I struggled in particular with the ethical Read More

Senescent cells after pregnancy may fuel postpartum breast cancer spread​Senescent cells after pregnancy may fuel postpartum breast cancer spread 

Postpartum breast cancer is diagnosed five to ten years after giving birth. It is associated with a higher risk of metastasis and a lower survival rate compared with women who have not been pregnant or those diagnosed during pregnancy. A team from the Institut Pasteur set out to understand the mammary gland mechanisms involved in tumor formation during involution, a major tissue remodeling process that occurs after pregnancy.

Risk for nonscarring hair loss increased in association with GLP-1 receptor agonist use​Risk for nonscarring hair loss increased in association with GLP-1 receptor agonist use 

The risk for nonscarring hair loss (NSHL) is increased in association with glucagon-like peptide-1 receptor agonist (GLP-1 RA) use, according to a study published online Feb. 9 in the Journal of the American Academy of Dermatology. ​The risk for nonscarring hair loss (NSHL) is increased in association with glucagon-like peptide-1 receptor agonist (GLP-1 RA) use, Read More