New GLP-1 pill orforglipron outperforms oral semaglutide in yearlong diabetes trialNew GLP-1 pill orforglipron outperforms oral semaglutide in yearlong diabetes trial

A novel GLP-1 receptor agonist (RA) pill called orforglipron leads to a larger reduction in blood sugar levels after a year than the current available oral GLP-1 RA (semaglutide), finds a phase 3 randomized controlled trial published in The Lancet. Additionally, participants taking orforglipron had significantly greater reductions in body weight than those taking oral Read More
GLP-1 drugs combined with healthy lifestyle habits linked to reduced cardiovascular risk among diabetes patientsGLP-1 drugs combined with healthy lifestyle habits linked to reduced cardiovascular risk among diabetes patients

Individuals living with type 2 diabetes (T2D) had a significantly lower risk of poor cardiovascular health when they used a GLP-1 receptor agonist (GLP-1 RA) in combination with adhering to healthy lifestyle habits, according to a new study led by researchers at Harvard T.H. Chan School of Public Health and the Department of Veterans Affairs Read More
GLP-1 drugs combined with healthy lifestyle habits linked with reduced cardiovascular risk among diabetes patientsGLP-1 drugs combined with healthy lifestyle habits linked with reduced cardiovascular risk among diabetes patients

Home Chronic Diseases GLP-1 drugs combined with healthy lifestyle habits linked with reduced cardiovascular risk among diabetes patients By Maya Brownstein February 25, 2026 Hide caption Show caption aprott / iStock Jump to Section Share Post LinkedIn Facebook WhatsApp Email Copy link For immediate release: February 25, 2026 Boston, MA—Individuals living with type 2 diabetes Read More
‘Father Knows Best’ star Lauren Chapin dead at 80 after 5-year cancer battle’Father Knows Best’ star Lauren Chapin dead at 80 after 5-year cancer battle

Lauren Chapin, the beloved “Father Knows Best” star who played Kathy “Kitten” Anderson, has died at age 80 after a five-year cancer battle, her son announced.
Semaglutide Not Linked to Depression Symptoms in People With HIVSemaglutide Not Linked to Depression Symptoms in People With HIV

(MedPage Today) — DENVER — People with HIV didn’t have a significant rise in depressive symptoms after starting semaglutide (Ozempic, Wegovy, Rybelsus) for diabetes or weight loss, according to a nine-site observational study. After a median… (MedPage Today) — DENVER — People with HIV didn’t have a significant rise in depressive symptoms after starting Read More
How an anti-obesity drug improves metabolism beyond weight lossHow an anti-obesity drug improves metabolism beyond weight loss

Tirzepatide is one of the drugs that has revolutionized the treatment of obesity and other conditions such as diabetes in recent years. Despite its clinical success, its precise molecular and cellular mechanisms are still not fully understood. A study in mice shows that the drug has a direct impact on improving metabolism by activating brown adipose tissue, a type of fat specialized in energy expenditure.
Novo Nordisk to slash Wegovy and Ozempic prices starting in 2027Novo Nordisk to slash Wegovy and Ozempic prices starting in 2027

Starting in 2027, the Danish pharma firm will sell its weight-loss and diabetes drugs for $675 per month. Starting in 2027, the Danish pharma firm will sell its weight-loss and diabetes drugs for $675 per month.
STAT+: Pharmalittle: We’re reading about an FDA plan for ultra-rare drugs, Novo cutting GLP-1 drug prices, and moreSTAT+: Pharmalittle: We’re reading about an FDA plan for ultra-rare drugs, Novo cutting GLP-1 drug prices, and more

Rise and shine, everyone, another busy day is on the way. And it is getting off to a good start here on the Pharmalot campus, where we have clear blue skies and chilly breezes greeting us today. Who could ask for anything more? Actually, we could — it is time to reheat the tea kettle for Read More
Novo Nordisk to halve U.S. list price of Wegovy from 2027Novo Nordisk to halve U.S. list price of Wegovy from 2027

Novo Nordisk will slash U.S. list prices of its blockbuster diabetes and weight-loss drugs Ozempic and Wegovy by up to 50% starting next year, the Danish drugmaker said on Tuesday Novo Nordisk will slash U.S. list prices of its blockbuster diabetes and weight-loss drugs Ozempic and Wegovy by up to 50% starting next year, the Read More
Biden friends voice concern over increased fatigue amid cancer battle: reportBiden friends voice concern over increased fatigue amid cancer battle: report

Joe Biden continues radiation therapy for Stage 4 prostate cancer that has metastasized to bone, with aides saying the 83-year-old former president remains active and engaged.