GLP-1 receptor agonists linked to lower mortality for patients with brain metastases, T2DMGLP-1 receptor agonists linked to lower mortality for patients with brain metastases, T2DM

For patients with cancer and brain metastases (BM) and type 2 diabetes (T2D), glucagon-like peptide-1 receptor agonist (GLP-1 RA) use is associated with significantly lower all-cause mortality, according to a research letter published online March 11 in JAMA Network Open. For patients with cancer and brain metastases (BM) and type 2 diabetes (T2D), glucagon-like peptide-1 Read More
What happens when patients stop taking GLP-1 drugs? New study reveals real world insightsWhat happens when patients stop taking GLP-1 drugs? New study reveals real world insights

As the use of injectable GLP-1 drugs continues to rise, questions persist about what happens after patients stop taking them in real-world settings. A new Cleveland Clinic analysis of nearly 8,000 patients suggests that discontinuing semaglutide and tirzepatide, on average, does not lead to significant weight regain in clinical practice, as many patients later restart Read More
‘Mormon Wives’ star weighs just 99 pounds at 5′ 10″, admits GLP-1 addiction’Mormon Wives’ star weighs just 99 pounds at 5′ 10″, admits GLP-1 addiction

Reality TV star Layla Taylor revealed she’s been silently struggling with an eating disorder for years during the tumultuous season four of “The Secret Lives of Mormon Wives.” Taylor, 25, admitted she has been living with an eating disorder since high school. During an episode of the Utah-based show, Taylor said she’s been abusing GLP-1s Read More
A new triple negative breast cancer target: Why HORMAD1 could guide treatment choicesA new triple negative breast cancer target: Why HORMAD1 could guide treatment choices

A gene that is typically active only in reproductive cells may hold the key to new treatments for triple negative breast cancer, according to new research published in the journal Nature Communications. Scientists from the Breast Cancer Now Toby Robins Research Center at The Institute of Cancer Research, London (ICR) and the Breast Cancer Now Research Unit at King’s College London, have uncovered a new weakness in triple negative breast cancer linked to a gene called HORMAD1 and a way to target it.
Why Ozempic users are actually spending more on high-end chocolateWhy Ozempic users are actually spending more on high-end chocolate

Chocolate sales are rising faster among people using weight-loss drugs than in the rest of the population, according to a new report. Swiss chocolatier Lindt & Sprüngli cited data countering predictions that GLP-1 drugs would reduce interest in sweets. Semaglutide medications, like Ozempic and Wegovy, mimic the natural hormone GLP‑1 (glucagon‑like peptide‑1), while tirzepatides (such Read More
Berberine as a natural Ozempic? An analysis of a popular mythBerberine as a natural Ozempic? An analysis of a popular myth

In recent years, berberine has increasingly appeared in the public sphere as a “natural way” to improve metabolism. In social media, it is sometimes compared to incretin drugs and even referred to as “plant-based Ozempic.” Such comparisons suggest a simple mechanism of action and predictable effects. In recent years, berberine has increasingly appeared in the Read More
Impurity in Some Compounded Tirzepatide ‘Potentially Dangerous,’ Eli Lilly WarnsImpurity in Some Compounded Tirzepatide ‘Potentially Dangerous,’ Eli Lilly Warns

(MedPage Today) — Compounded versions of tirzepatide (Mounjaro, Zepbound) containing vitamin B12 pose a potential safety risk to the public, Eli Lilly warned in an open letter on Thursday. Following laboratory testing, the drugmaker said it uncovered… (MedPage Today) — Compounded versions of tirzepatide (Mounjaro, Zepbound) containing vitamin B12 pose a potential safety risk Read More
Police probe breast cancer treatment allegationsPolice probe breast cancer treatment allegations

The inquiry is being held over concerns of poor care at the County Durham and Darlington trust.
STAT+: The FDA is targeting telehealth marketing of GLP-1 drugs. Who’s prescribing them?STAT+: The FDA is targeting telehealth marketing of GLP-1 drugs. Who’s prescribing them?

The Food and Drug Administration is cracking down on telehealth companies’ marketing of compounded versions of weight loss drugs. In recent months, the agency has warned them against implying that their products are FDA approved, or that they themselves manufacture the products. But those companies may not be the only ones under the microscope. The Read More
Breast cancer stage at diagnosis differs sharply across rural US regionsBreast cancer stage at diagnosis differs sharply across rural US regions

Where a woman lives significantly affects whether her breast cancer is diagnosed at an early or late stage, according to a national analysis published in the Journal of the American College of Surgeons (JACS). Researchers found prominent geographic variations within rural regions across the United States, and that race and insurance status also strongly influenced a woman’s stage of breast cancer at diagnosis.