Semaglutide Has Disproportionate Suicidality Signal, Analysis FindsSemaglutide Has Disproportionate Suicidality Signal, Analysis Finds

(MedPage Today) — A disproportionality analysis based on reports in a World Health Organization (WHO) database suggested a suicidal ideation signal with the GLP-1 receptor agonist semaglutide (Ozempic, Rybelsus, Wegovy). Between 2000 and 2023… (MedPage Today) — A disproportionality analysis based on reports in a World Health Organization (WHO) database suggested a suicidal ideation Read More
Zepbound Can Prevent Diabetes; Menopause and Cognition; Tandem’s Insulin Pump UpdateZepbound Can Prevent Diabetes; Menopause and Cognition; Tandem’s Insulin Pump Update

(MedPage Today) — In a phase III study of adults with pre-diabetes and obesity or overweight, tirzepatide (Zepbound) reduced the risk of developing type 2 diabetes by 94% over a 3-year period, Eli Lilly announced. In related news, real-world… (MedPage Today) — In a phase III study of adults with pre-diabetes and obesity or Read More
Mounjaro, Zepbound cut odds for diabetes by 94% in at-risk people, study findsMounjaro, Zepbound cut odds for diabetes by 94% in at-risk people, study finds

Tirzepatide, the blockbuster GLP-1 medicine known as Mounjaro for diabetes and Zepbound for weight loss, cut the odds that an obese, prediabetic person will develop diabetes by 94%, a new trial shows. Tirzepatide, the blockbuster GLP-1 medicine known as Mounjaro for diabetes and Zepbound for weight loss, cut the odds that an obese, prediabetic person Read More
Disproportionality Analysis From WHO Data on Semaglutide, Liraglutide, and SuicidalityDisproportionality Analysis From WHO Data on Semaglutide, Liraglutide, and Suicidality

This case control study evaluates potential signals for suicidal and self-injurious adverse drug reactions associated with semaglutide and liraglutide. This case control study evaluates potential signals for suicidal and self-injurious adverse drug reactions associated with semaglutide and liraglutide.
GLP-1 Receptor Agonists and SuicidalityGLP-1 Receptor Agonists and Suicidality

Psychiatry Psychiatry
Clinical Outcomes of Tirzepatide or GLP-1 Receptor Agonists in Type 2 DiabetesClinical Outcomes of Tirzepatide or GLP-1 Receptor Agonists in Type 2 Diabetes

This cohort study investigates the risks of mortality and adverse cardiovascular and kidney outcomes among individuals with type 2 diabetes taking tirzepatide vs glucagon-like peptide 1 receptor agonists. This cohort study investigates the risks of mortality and adverse cardiovascular and kidney outcomes among individuals with type 2 diabetes taking tirzepatide vs glucagon-like peptide 1 receptor Read More
Popularity of Ozempic and Wegovy among privately insured patients may worsen disparities, suggests studyPopularity of Ozempic and Wegovy among privately insured patients may worsen disparities, suggests study

A USC study suggests that publicly insured individuals who are most likely to benefit from new drugs for diabetes and obesity are less likely to get them than those with private insurance. A USC study suggests that publicly insured individuals who are most likely to benefit from new drugs for diabetes and obesity are less Read More
Prescription Fills for Semaglutide Products by Payment MethodPrescription Fills for Semaglutide Products by Payment Method

This cross-sectional study examines trends in US prescription fills for semaglutide products by payment method between January 2021 and December 2023. This cross-sectional study examines trends in US prescription fills for semaglutide products by payment method between January 2021 and December 2023.
Safety and Risk Assessment of No-Prescription Online Semaglutide PurchasesSafety and Risk Assessment of No-Prescription Online Semaglutide Purchases
This qualitative study assesses the quality, amount of active ingredient, and characteristics associated with counterfeiting of semaglutide purchased from illegal online pharmacies without a prescription. This qualitative study assesses the quality, amount of active ingredient, and characteristics associated with counterfeiting of semaglutide purchased from illegal online pharmacies without a prescription.
Ozempic and Wegovy could help people quit smokingOzempic and Wegovy could help people quit smoking

Semaglutide-based medicines such as Ozempic and Wegovy, which can help people lose weight, may also reduce tobacco cravings Semaglutide-based medicines such as Ozempic and Wegovy, which can help people lose weight, may also reduce tobacco cravings